Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

• The usual starting dose is 50mg, taken approximately one hour before sexual activity.
• Dosage can be adjusted depending on individual response and tolerability.
• Take only one tablet in 24 hours, with or without food.
• Avoid grapefruit juice, as it can increase the risk of side effects.
• A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

• Headache
• Flushing
• Nasal congestion
• Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

• Taking nitrates for chest pain
• With severe heart or liver conditions
• Under 18 years of age
• With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

• Nitrates
• Alpha-blockers
• Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

• Generic versions are more affordable than branded Viagra.
• Supplied by licensed UK pharmacies such as Online Chemist.
• Avoid counterfeit products from unregulated websites.

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Product description

This is the original prescription medication for ED, manufactured by Pfizer. It is approved for use by regulatory agencies in the UK and most other countries. This medicine contains 50mg of the active ingredient, which is sildenafil citrate. This medication works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Patient information leaflet

The Patient Information Leaflet includes:

What is sildenafil?

Sildenafil is the generic version of Viagra, a prescription drug that is used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.

Sildenafil works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Viagra 100mg tablet contains an active component such as Sildenafil. This medication is used to treat erectile dysfunction (ED) in men. It contains the active ingredient sildenafil citrate, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It increases blood flow to the penis during sexual stimulation, which helps men achieve and maintain an erection. Viagra may have side effects, including headache, flushing, dizziness, upset stomach, nasal congestion, and vision changes. It should not be taken with certain medications or conditions, so it's crucial to consult a healthcare professional before using it. Erectile dysfunction can have a profound impact on a man's self-esteem and quality of life. By addressing ED, this medication can help improve a person's sense of well-being and overall happiness.

Individuals with a history of, such as heart problems (angina, heart failure, irregular heartbeats) or recent heart attack, should exercise caution when using Viagra. The sexual activity itself can strain the heart and can further increase the strain by increasing blood flow. Consult with a healthcare professional to assess the risks and benefits in such cases. This medication can cause a mild decrease in blood pressure. Caution is advised for individuals with low blood pressure or those taking medications that lower blood pressure, as combining these can lead to potentially harmful interactions. People with severe liver or kidney disease may experience slower elimination of Viagra from the body, leading to a prolonged effect. Dosage adjustments may be necessary in such cases.

What is Sildenafil?: Sildenafil is a, a PDE5 inhibitor, which works by relaxing the blood vessels, thereby allowing blood to flow more easily to the penis. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil increases the blood flow to the penis during sexual activity by relaxing the coronary vessels, allowing for easier blood flow, and enhancing the relaxation of the walls of the arteries, thereby reducing strain on the penis and promoting a hard and erect penis.

Sildenafil works by inhibiting the action of PDE5, which leads to the reduction in the levels of cyclic guanosine monophosphate (cGMP). This smooth muscle relaxation allows the blood to flow more freely through the penis, providing a firm and long-lasting erection during sexual activity. As a result, it aids in erectile dysfunction (ED).

The recommended starting dose of Sildenafil is 100mg, butmidt healthcare provider, can prescribe lower doses, such as 25mg and 50mg, depending on a doctor's prescription. Dosage adjustments may be necessary in some cases. People with severe liver or kidney disease may experience slower elimination of Sildenafil from the body, leading to a prolonged effect. Consult with a healthcare professional before using this medication for this condition typically requires regular monitoring by a doctor.

The time it takes to feel full and active may depend on the individual and the age. It may take up to 4 hours to feel the benefits, depending on the severity of the erectile dysfunction. Dehydration can affect the time it takes to work, as happens in men whoilds (symptoms of erectile dysfunction) every day with water or acid.

As with all medications, follow your healthcare provider's instructions about your medicines. Dehydration can amplify the benefits, leading to a prolonged erection.

Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

consultation with doctor

Alpha-blockers (such as doxazosin or tamsulosin) have been shown to cause dangerous drops in blood pressure when used with Sildenafil. Verify with your doctor if you are using alpha-blockers to boost your blood pressure.

Pde7 inhibitors can interact with Sildenafil

Some PDE7 inhibitors that have been tested against Sildenafil can cause a dangerous drop in blood pressure. In the above medical scenario, be aware that conflicting results may occur when using Sildenafil with PDE-enzyme inhibitors. Prior to starting, verify that you are using PDE-enzyme inhibitors when using Sildenafil together with Sildenafil 20mg. If you are using PDE-enzyme inhibitors together with Sildenafil, it will cause a dangerous drop in blood pressure. Proper storage and disposal of Sildenafil should never be a priority for you.

To reduce the risk of side effects, always consult your doctor or pharmacist before using Sildenafil with PDE-enzyme inhibitors.

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Zambia ( Namuedoc)- Consult doctor+ $ 0.50 per pill

- Use only Sildenafil+if co-administration not recommendedor taken-do not use with other ED medicationsconsult doctoravoid if possibledo not use with nitratesif you are taking guanylate cyclase stimulatorskeep Sildenafil activeConsult doctorRead the PDE-enzyme list before using Sildenafil

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Uses of Sildenafil

Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.

Therapeutic Category

Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors

How Sildenafil works

Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.

Common side effects of Sildenafil

• headache
• flushing
• indigestion, diarrhoea
• pain in the arms or legs
• vision problems
• flu-like symptoms, inflammation of the sinuses, fluid retention
• difficulty in sleeping, anxiety, shaking
• sensation of pins and needles
• vertigo (spinning sensation)
• nosebleed, runny nose, cough, stuffy nose
• nausea, vomiting, stomach inflammation, heartburn, piles, abdominal distension, dry mouth, diarrhea
• hair loss
• skin redness, night sweats
• muscle pain, back pain
• increased erections

When to consult your doctor

Consult your doctor if you experience:

• prolonged or painful erection (priapism)
• sudden decline or loss of vision
• fits or seizures
• pneumonia, abnormal heartbeat, chest pain, fainting
• infections (viral infection of the gut, urinary tract infections and tooth cavities)
• fits, hearing impairment inflammation of digestive tract

Health Tips for Sildenafil

• Sildenafil is not suitable for use in women
• Sildenafil is generally more effective when taken on an empty stomach
• Avoid consumption of alcohol or grapefruit juice while taking Sildenafil as it may increase its side effects
• Avoid using recreational drugs (like amyl nitrate, etc.) while taking sildenafil as it may cause a dangerous drop in blood pressure
• Sildenafil should not be taken more than once in a 24-hour period
• Before taking Sildenafil, inform your doctor if you have any liver, kidney, or heart problems

Inauthored report accepted withree in in

Originally accepted as ofMay 25th, 2023

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Closed access toPharmacy forademic placement only

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This document does not offer protection against hostile, upset, irritated, irritated, irritated, irritated, irritated, or any other complaints from academic placement.

Please refrain from having any eating disorder, stomach ulcers, stomach cancer, heart disease, blood clots, asthma, diabetes or thyroid problems. Eat less and exercise more regularly.

Sildenafil may cause dizziness, lightheadedness, headache, flushing, nasal congestion, heartburn, sleep problems, skin rash, heartburn, skin blisters or itching, and menstrual cramps. If you experience any of these symptoms, stop taking sildenafil and call your doctor immediately.

In rare cases, sildenafil has been associated with an increased risk of common cold, flu, severe generalised new ageiness, weight gain, and increase in blood pressure.

Product NameSildenafil 100mgGeneric nameDosage formPacks strength

Sildenafil tablets 50mg, 100mg, 150mg, 200mg, 300mg, 400mg, and 50mg are used for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Sildenafil is a selective phosphodiesterase 5 (PDE5) inhibitor. It works by relaxing blood vessels in the penis, allowing increased blood flow during sexual stimulation. It works to treat ED by increasing the amount of blood that flows to the penis, helping men achieve and maintain an erection.

Sildenafil 50mg Tablet is a prescription medication that is available only with a doctor's prescription. It should only be used under the supervision of a healthcare professional who can assess your medical history, current health, and the possibility of certain medications and disorders.

Sildenafil 50mg 100mg Tab 10s

It works to treat PAH by relaxing blood vessels in the lungs, which helps to improve exercise capacity in people with PAH.

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Sildenafil 50mg tablet is a prescription medication that is available only with a doctor's prescription.